This course outlines the basic principles of clinical and laboratory hematology and shows how manifestations of blood diseases can be explained by new knowledge of the disease processes. It focuses on concepts established during immunology and pathology in the consideration of the impact of diseases of the circulating elements of blood
Course contents:
1. Organization and function of the blood forming organs, the structure and functions of circulating elements and the basics of hematology.
2. Common hematologic disorders, their etiology, defining characteristics, diagnosis and treatment.
3. Benign and malignant disorders of the white blood cells with respect to diagnosis and etiology.
4. Laboratory techniques used in hematology.
5. Case study presentations and blood film of hematological diseases
Hematology represents the understanding of blood formation form the bone marrow and other organs such as liver and spleen and their journey to the blood circulation. The anatomy, physiology, and functions of the hematopoietic system are all involved in the production of blood. Hematologic activities, such as red blood cell formation and the clotting cascade, require a complex series of events to allow good health and homeostasis.
Immunology background as a well as molecular biology help the students to understand modulation of immune cells as well chromosomal mutations that happen in several leukemias and how we can immunophenotype these diseases according to antigen alterations on immune cells together with the aid of molecular techniques.
1. Clinical Laboratory Hematology, by Shirlyn B Mckenzie, 3rd edition, 2014.
2. Hoffbrand's Essential Haematology, 7th Edition, 2015.
3. Selected articles on Hematology disorders and new updates on mechanistic as well therapeutic issues: www.Pubmed.com
4. Clinical Hematology Atlas, Bernadette F. Rodak, Jacqueline H. Carr, 4th Edition, Elsevier, 2013.
Activity | Percent (%) |
---|---|
Midterm exam | 30% |
multiple assignments | 20% |
Final | 50% |