This course concentrates on the basic and clinical science of the immune system and its relationship to other sciences and biological systems of mammals. This course will concentrate on function-structure relationship of the immune system and its components such as the lymphoid tissue and cells, the development and function of the immune system, as well as the clinical science of the immune system and its role in the prevention, causation and diagnosis of human diseases such as cancer, autoimmune disease and other topics.
The objective of this course is to learn about the component of the immune system as well as their functions. The student will learn about antigen presentation, humoral immune response, cellular immune response, inflammation, complement and cytokines. The student should known different categories of diseases related to the immune system such as hypersensitivity reactions and autoimmunity.
After this course the students should know the basic elements of immunology namely lymphocyte biology, antigen presentation, humoral, cellular, mucosal immune responses, inflammation, complement and cytokines. The student should be familiar with different categories of diseases related to the immune system and highlight the hypersensitivity reactions, autoimmunity and immunodeficiency diseases.
Intended Learning Outcomes of Course (ILOs)
a- Knowledge and Understanding:
a.1. Recognize the normal immune system.
a.2. Describe the mechanisms of innate immunity.
a.3. Recognize antigens, Immunoglobulins and describe antigen - antibody reactions.
a.4. Describe antigen presentation and the major histocompatibility complex.
a.5. Identify inflammation and the inflammatory response.
a.6. Recognize the humoral and cell mediated immune response
a.7. Describe the hypersensitivity reactions and immunodeficiency diseases.
a.8. Explain Immune tolerance and principles of autoimmunity
a.9.Describe the basics of Transplantation and tumor immunity
Immunology Male et al., 8th Ed. 2013.
Basic Immunology Abbas et. al. 3th 2013.
Published scientific papers.
Murphy et al. Janeway's Immunobiology, 8th Ed. 2011