Background: Artificial sweeteners (AS) are synthetic sugar substitutes that have sweetening potency hundreds of times more than the table sugar (sucrose). Artificial sweeteners are regarded as attractive alternatives to sugar as they add no calories to food intake. There are many hypotheses suggesting that AS may enhance appetite and cause weight gain.

Objective: To evaluate the effect of AS on food intake, fluid intake and body weight of mice.

Method: Acceptable daily intake of AS solutions were administered orally to different set of mice for four weeks. The body weight, food consumption and fluid intake were measured. At the same time, the effect of Zingiber officinale extracts (natural appetite suppressor), Thymus vulgaris extracts (natural appetite inducer) and cyproheptadine (an appetite stimulant drug) on body weight of mice was evaluated.

Results: Artificial sweeteners consumption cause insignificant changes in body weight (p>0.05). Although, the mean consumption of food and solutions varies significantly for some groups.

Conclusion: The consumption of AS has no significant effect on body weight and may contribute to weight maintenance and energy balance as substitutes to high caloric sugar.

Title

Journal of Biological Research

Publisher

Page press

Publisher Country

Italy

Indexing

Scopus

Impact Factor

0.8

Publication Type

Online only

Volume

--

Year

2020

Pages

--