Background: Rumex rothschildianus is the sole member of a unique section of the genus Rumex, in the family
Polygonaceae. This species is a very rare small dioecious annual, endemic to Palestine that is traditionally used as
food and for the treatment of various diseases. Therefore, the current investigation aimed to screen the chemical
constituents, antioxidants, anti-α-amylase, anti-α-glucosidase, antilipase, and cytotoxic effects of four solvents
fractions of R. rothschildianus leaves.