Abstract Background: T1DM is a significant chronic illness affecting children and young people globally, especially in low and middle income nations. In 2021, 4.4 percent of the Palestinian diabetic population would have T1DM, and few studies have focused on this group. The aim of this study is to picture the clinical and epidemiological features of T1DM attending Diabetic clinics in the North of Palestine. Methods: A cross-sectional descriptive study was conducted in diabetic centers in both Nablus and Ramallah cities among DM type I aged 18 years old or above from November 2020 to May 2021.Clinical and Epidemiological features were collected by reviewing medical files while missing data was completed by phone calls. We used the IBM SPSS Statistics for Windows, Version 20.0 (IBM Corp., Armonk, NY: IBM Corp) for statistical analyses. Frequencies and percentages and mean ± standard deviation (SD) to describe participants’ characteristics and clinical and epidemiological data were reported. Univariate analysis using Pearson Chi2 test (or Fisher exact test when appropriate) or independent t-test were used to evaluate the relation between the different independent variables and the diabetes control status (controlled versus uncontrolled). A p value less than 5% was set as a level of significance. Results: Of the 258 patients, 136 (52.7%) were females. The mean age (SD) was 27.62 (7.590). 147 (59.8%) hold a university degree, 157 (63.1%) of participants were unemployed and 164 (64.9%) were unmarried. 123 (68.1%) had never smoked and only 35 (20%) reported being physically inactive. 196 (71.7%) of our patients showed a positive family history of DM. The mean (SD) of BMI was 23.218 ± 3.447 and (60.9%) had normal weight. The mean (SD) HbA1C was (9.6912 ±2.309). 206 (79.5%) had uncontrolled diabetes (HbA1C <7.5). 179 (97%) depend only on insulin injections without using oral agents with a mean duration of treatment (mean, SD) of 10.29 ± 8.768 and being the Glucocheck the conventional method used by patients to monitor their blood glucose level (70.2%). 224 (87.8%) had no complications, while (11%) had retinopathy. The bivariate analysis showed a statistically significant association between diabetic control and educational level in favor of high educational level (p value = 0.013). Conclusion: This is the first research to describe T1DM patients’ characteristics in North of Palestine showing that our patients are mostly females with a high educational level and a positive family history of disease but no partner in life, job, or any inclination toward smoking Low educational levels increase the risk of having uncontrolled diabetes, so efforts must be made to raise the level of education. Better documentation of diabetes data is needed to improve the lack of research in this subject area in Palestine.