This study aims to investigate the effects of the COVID-19 pandemic on domestic tourism in the Nablus City located in the West Bank, Palestine. The data for this study are collected using the questionnaire method as a research instrument. Three sets of questionnaires were designed to target three different groups of people: tourists or visitors, employees of tourism facilities, and owners of tourism facilities. These three questionnaires were then distributed online to the participants. The responses from the participants were then collected through email and a descriptive analysis was carried out for a total of 263 valid questionnaires based on the responses. The findings of this study have shown that domestic tourism in the West Bank was negatively affect-ed because of the COVID-19 pandemic. This study also revealed that the average number of employees in the tourism facilities decreased significantly during the pandemic to 22%. The aver-age number of tourists also decreased to around 5%, while 20% of tourists’ facilities were closed. Also, the lifestyle of locals has changed significantly. Based on the findings, this study also presented a few suggestions to assist the recovery of domestic tourism in Nablus city. These suggestions include creating a program led by the government and the private sector to support small and medium tourism enterprises.