Cancer-related post-treatment pain and its impact on treatment satisfaction with medication in women with breast cancer: a cross-sectional study from Palestine
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Original research
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Abstract    Background Pain after therapy is an important clinical problem in patients with breast cancer. Unfortunately, cancer patients have a lower quality of life due to inadequate treatment of posttreatment pain; therefore, improving medication management plans and palliative care has become one of the most important targets of cancer therapy. Therefore, the current study aimed to examine the impact of posttreatment pain on medication satisfaction in patients with various stages of breast cancer in Palestine. Methods A cross-sectional analytical study was conducted et al.-Watani Hospital and An-Najah National University Hospital in the Nablus area. Using the Brief Pain Inventory (BPI), the intensity and interference of pain were evaluated. In addition, patients’ satisfaction with cancer management medications was measured using the Treatment Satisfaction Questionnaire for Medication (TSQM). Results Two hundred fifty-four patients were included in this study. All were women, with a mean ± SD age of 53.1±10.7 years. The median score for pain severity was 7.0. Pain in the lower extremities was the most reported location. There was a negative association between the global satisfaction domain and the presence of posttreatment pain (p<0.001). Furthermore, signifcant diferences and negative correlations were found between global satisfaction and posttreatment pain on the day of the interview (p=0.001), pain medication (p<0.001), paracetamol use (p<0.001), and the presence of side efects (p=0.003). There were signifcant negative correlations (p<0.05) between pain severity and interference with efectiveness (r=-0.258, -0.319, respectively), side efects (r=-0.414, -0.514, respectively), convenience (r=-0.274, -0.307, respectively), and global satisfaction domain scores (r=-0.293, -0.287, respectively). Exposure to chemotherapy was the only signifcant positive correlation with global satisfaction (p=0.007). The regression analysis results indicated an independent association between chemotherapy use and a higher global satisfaction score (p=0.011). Conclusions Patients with posttreatment pain, side efects, and greater interference of pain with their functioning had lower satisfaction scores. Therefore, better management of their treatment medications, side efects, and pain medications is recommended to enhance their satisfaction and quality of life. Several aspects of palliative care should be organized to improve the patient's satisfaction and quality of life in addition to conducting longitudinal studies to evaluate the pain and satisfaction of diferent types of cancers. Keywords Breast cancer · Posttreatment pain · Patient satisfaction with medication · Chemotherapy · Hormonal therapy · Biological therapy · Side efects

Journal
Title
Supportive Care in Cancer
Publisher
Springer Nature
Publisher Country
United Kingdom
Indexing
Scopus
Impact Factor
None
Publication Type
Both (Printed and Online)
Volume
31
Year
2023
Pages
15