Introduction. Volatile oils (VOs) have been commonly used in cosmetics and food as fragrances, favoring, and preservative agents or in alternative medicine for their therapeutic efects. Tis necessitates investigating those plants and their VOs. Tis study was conducted to investigate the chemical compositions of the VOs of Micromeria fruticosa serpyllifolia growing widely in three regions in Palestine (i.e., Hebron, Ramallah, and Nablus districts representing south, middle, and north of West Bank). Aferwards, VOs were subjected to in vitro screening and their enzymatic properties were compared. Methods. Te analysis of chemical components of VOs was performed by gas chromatography coupled with mass spectrometry (GC-MS). Te antilipase activity was evaluated using porcine pancreatic lipase and p-nitrophenyl butyrate. Te antiamylase activity was assessed using porcine pancreatic �- amylase, starch, and 3,5-dinitrosalicylic. Results. Plant extracts yield range was 0.67 to 0.99 w/w%. GC-MS analysis showed the high percentages of oxygenated components in the range of 86.1-89.88% and nonoxygenated components in the range of 4.38- 4.71%. Seven components were observed, pulegone was the most abundant component in the three samples in the range of 74.43- 86.04%, and isomenthone was the second most abundant component with the range of 3.16-14.41%. Te sample collected from Nablus showed the most potent antilipase and antiamylase activity with IC50 values of 39.81 �g/mL and 3.31 �g/mL, respectively. Conclusions. Te study showed that Micromeria fruticosa serpyllifolia volatile oils samples from diferent regions in Palestine contained diferent proportions of phytochemicals which provided diferent potential biological activities such as antiobesity and antidiabetes activities that were in line with traditional uses of the plant extracts. Te plant extracts showed higher antilipase and antiamy

Title

BioMed Research International

Publisher

Hidawi

Publisher Country

United Kingdom

Indexing

Thomson Reuters

Impact Factor

2.85

Publication Type

Online only

Volume

--

Year

2018

Pages

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