In response to the United Nations’ declaration of the Second Decade of Action for Road Safety, countries have prepared their national road safety strategies with the target of reducing deaths and injuries by half in 2030. This paper intends to present the outcome of a study that utilises a comparative methodological approach to examine what a developed country (Australia) and a developing country (Palestine) have in common or differ in their prepared road safety strategies. The results show that there are similarities in the general themes, yet major differences exist in the goals, strategies, and actions. Such differences are mainly related to the specificities of each country. Recommendations include reducing gaps in road safety indicators between the two countries benefiting from the successes of developed countries, transferring knowledge, and supporting the less developed countries to overcome road safety challenges to achieve the common value of maintaining human life and health.