Stabilization of poloxamine and poloxamer block copolymer complexes in chlorinated organic solvents – mathematical modelling
Publication Type
Original research
Authors

To develop amathematical model describing the behavior of chromophore complexes, the main factors influencing the stability of poloxamine and poloxamer complexes were determined. Gel permeation chromatography, ultraviolet absorbance measurements and FT-IR were used for the analysis. It was found that the studied complexes in chlorinated organic solvents are unstable in the presence of oxygen, air, or wa-ter. The developed mathematical model allows for more effective planning and execution of experiments due to the possibility of predicting UV absorption based on the distribution of complexes in chlorinated solvents.Keywords: poloxamines, poloxamers, block copolymers, ammonium ferrothiocyanate, colorimetric analysis, mathematical modeling.

Journal
Title
Polimery
Publisher
Sieć Badawcza Łukasiewicz - Instytut Chemii Przemysłowej imienia Profesora Ignacego Mościckiego
Publisher Country
Poland
Indexing
Thomson Reuters
Impact Factor
1.1
Publication Type
Both (Printed and Online)
Volume
9
Year
2024
Pages
473