Unexpected triaxial preferences in some all-syn 1,3,5-trifluorocyclohexanes
Publication Type
Original research
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Theory and solution NMR indicate that all-syn 1,3,5-trifluorocyclohexane 5 adopts the expected tri-equatorial conformation, however in the solid state the more polar triaxial conformation is observed. This and the favoured conformations of substituted (Me, OMe, NH(CO)Me, NHBoc) derivatives of 5 are investigated to explore triaxial C–F preferences.

 

Journal
Title
Chem. Commun., 2022, 58, 12855-12858
Publisher
RSC
Publisher Country
United Kingdom
Indexing
Thomson Reuters
Impact Factor
4.3
Publication Type
Both (Printed and Online)
Volume
58
Year
2022
Pages
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