Synthesis and Characterization of Some Antifungal Active Hydrazones From Combined of Several Functionalized Hydrazides With Di-2-Pyridyl Ketone
- Publication Type
- Original research
- Authors
Pyridlhydrazone derivatives [1-5] were synthesized for the first time by condensation of di-2-pyridyl ketone with different hydrazides individually. The corresponding solid phase hydrazide-hydrazones were collected from acidic-ethanolic medium after 8-10 hours of reflux in very good to excellent yields and purified twice by ethanol/water re-crystallization process. All the synthesized compounds are characterized by IR, 1H and 13C NMR, FAB-MS and other physical analyses tests. The microbiological antifungal activity was carried out toward Trichophyton mentagrophytes, Microsporum canis and Trichophyton rubrum.
Journal
- Title
- Journal of Saudi Chemical Society
- Publisher
- --
- Publisher Country
- Palestine
- Publication Type
- Both (Printed and Online)
- Volume
- --
- Year
- 2007
- Pages
- --