A Synthetic Approach for the Preparation of Rigid Analogs of 1,3-Dipropyl-7-methyl-8-aryl/heteroarylstyryl Xanthines
- Publication Type
- Original research
- Authors
- Abdel Zaid Nasser
- Pier Giovanni Baraldi
- Francesca Fruttarolo
- Mojgan Aghazadeh Tabrizi
- Maria del Carmen Nuñez
- Giampiero Spalluto
Tethering the N-8-substituents of N-8-substituted styryl xanthine to N-7 has resulted in a series of conformationally constrained styryl xanthine analogs having the general formula 8. These new compounds have also been evaluated in order to investigate if the A2A adenosine receptor would be able to tolerate such a modification.
Journal
- Title
- Synthesis (5): 0773-0777
- Publisher
- --
- Publisher Country
- Palestine
- Publication Type
- Both (Printed and Online)
- Volume
- --
- Year
- 2001
- Pages
- --