HIV-1 Co-Receptor CCR5 And CCR2 Mutations Among Greeks
- Publication Type
- Original research
- Authors
- Ghaleb M. Adwan
- Anna Papa
- Evagelia Papadimitriou
- Stella Alexiou
- Jonathan P. Clewley
- Ioannis Ntoutsos
- Nikos Malissiovas
- Antonis Antoniadis
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The frequency of CCR5 and CCR2 alleles in human immunodeficiency virus (HIV)-positive and HIV-negative populations of Northern Greece was investigated. The frequency of the CCR5v32 allele among the HIV-negative subjects was 0.052, while it was approximately twofold lower among the seropositives, suggesting that the heterozygous genotype confers a partial resistance to the HIV infection. No significant difference in CCR2 allele frequency between the two groups was observed.
Journal
- Title
- FEMS Immunology and Medical Microbiology 28 (2000) 87-89
- Publisher
- --
- Publisher Country
- Palestine
- Publication Type
- Both (Printed and Online)
- Volume
- --
- Year
- 2000
- Pages
- --