PSA and Testosterone Serum Levels in The Middle East; Is There a Difference?
Publication Type
Conference Paper

Objective: To evaluate the difference between testosterone and total prostate
specific antigen (TPSA) serum levels between Arabic and Turkish people in the Middle
Material and methods: The study included 3 groups of healthy men; Group I
included 119 patients with a mean age of 52.73±7.53 years from east of Turkey.
Group II consisted of 196 patients with a mean age of 50.32±7.84 years from west
of Turkey. Group III consisted of 388, with mean age of 51±6 years from west bank
in Palestine. The mean values of PSA and testosterone were calculated for each groups
and a comparison were carried out. The relationships among testosterone and TPSA
levels and patients’ age were investigated.
Results: The mean TPSA levels for Group I, Group II and group III were 1.11±0.78
ng/mL and 1.75±1.06 ng/mL and 1.1+8 ng/ml respectively (p=0.5, p=0.7, p=0.8
respectively). The mean testosterone levels in Group I (386.4±154.6 ng/dL), Group II
(383.9±170.6 ng/dL) and group III (380±230 ng/L) showed no significant difference
(p=0.89, p=0.29, p=0.7). In Group I there was a positive correlation between age of
the patients and testosterone level (r=0.22, p=0.015); however, in Group II, and group
III there were significant negative correlation between age and serum testosterone
levels (r=-0.16, p=0.022 and r=-0.29, p=0.01). Serum testosterone level showed no
significant correlation with TPSA level in all groups.
Conclusion: Testosterone or TPSA levels did not change among the groups.
However, the effect of age on testosterone levels varies according to different
geographical regions. 

Conference Title
23rd Turkish National Urology Meeting, 2014, Antalya
Conference Country
Conference Date
Oct. 16, 2014 - Oct. 16, 2014
Conference Sponsor
Turkish association of urology