Synthesis and Biological Activities of a Novel Naringin based Heterocyclic Derivatives
- Publication Type
- Conference Paper
- Authors
A number of naringin based heterocyclic derivatives dioxolane and imidazolidine have been synthesized and
evaluated for their antioxidant and biological activities. The chemical structures of the newly synthesized
compounds were verified on the basis of spectral and elemental methods of analysis. Investigation of
antibacterial activity of these compounds was determined by measuring MIC value using broth micro dilution
method for Gram-positive and Gram-negative bacteria, among the various synthesized compounds. Dioxolane
showed the highest antibacterial activity with minimal inhibitory concentration (MIC) of 0.125mg/ml, in
addition this compound exhibit the best antioxidant activity with inhibition concentration (IC50) of 18.7 μg/mL,
compared with other semi synthetic derivative
Conference
- Conference Title
- Fourth Conference on Biotechnology research and application in Palestine
- Conference Country
- Palestine
- Conference Date
- March 21, 2016 - March 21, 2016
- Conference Sponsor
- The Arab American University, Jenin,Palestine