Synthesis and Biological Activities of a Novel Naringin based Heterocyclic Derivatives
Publication Type
Conference Paper
A number of naringin based heterocyclic derivatives dioxolane and imidazolidine have been synthesized and evaluated for their antioxidant and biological activities. The chemical structures of the newly synthesized compounds were verified on the basis of spectral and elemental methods of analysis. Investigation of antibacterial activity of these compounds was determined by measuring MIC value using broth micro dilution method for Gram-positive and Gram-negative bacteria, among the various synthesized compounds. Dioxolane showed the highest antibacterial activity with minimal inhibitory concentration (MIC) of 0.125mg/ml, in addition this compound exhibit the best antioxidant activity with inhibition concentration (IC50) of 18.7 μg/mL, compared with other semi synthetic derivative
Conference Title
Fourth Conference on Biotechnology research and application in Palestine
Conference Country
Conference Date
March 21, 2016 - March 21, 2016
Conference Sponsor
The Arab American University, Jenin,Palestine