Derivatives of 1,3,4-oxadiazole exhibit a broad spectrum of pharmaceutical applications
such as antibacterial, anticonvulsant (Taha et al., 2016), anti-inflammatory, anticancer,
analgesic and fungicidal. As a part of our ongoing research on such molecules (Yasser et
al., 2016) we report herein on the synthesis and crystal structure of the title compound
(Fig. 1).
The molecule is approximately planar as indicated by the dihedral angle value of
8.64 (10) between the aromatic rings. The methoxy group lies almost in the plane of the
phenyl ring as indicated by the torsion angle value of 5.1 (3) for C9—O2—C5—C6.
The crystal structure features inversion-related dimers linked by pairs of N—H  N
hydrogen bonds generating R22
(8) loops (Table 1 and Fig. 2). A further N—H  N
hydrogen bond links the dimers into (100) sheets.
Synthesis

Title

IUCrData

Publisher

International Union of Crystallography

Publisher Country

United Kingdom

Publication Type

Prtinted only

Volume

1

Year

2016

Pages

1-6