Menthol is widely used as a fragrance and flavor in the food and cosmetic industries. It is also used in the medical and
pharmaceutical fields for its various biological effects. Gas chromatography (GC) is considered to be a sensitive method for the
analysis of menthol. GC chromatographic separation was developed using capillary column (VF-624) and a flame ionization
detector (FID). The method was validated as per ICH guidelines for various parameters such as precision, linearity, accuracy,
solution stability, robustness, limit of detection, and quantification. The tested validation parameters were found to be within
acceptable limits. The method was successfully applied for the quantification of menthol in suppositories formulations. Quality
control departments and official pharmacopeias can use our developedmethod in the analysis of menthol in pharmaceutical dosage
formulation and raw material.

Title

International Journal of Analytical Chemistry

Publisher

Hindawi Limited

Publisher Country

Egypt

Indexing

Thomson Reuters

Impact Factor

0.901

Publication Type

Both (Printed and Online)

Volume

2018

Year

2018

Pages

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