Aims: This study was conducted to evaluate the genotoxic effects of fruit and leaf ethanolic extracts
of Ecaballium elateruim on clinical and reference strains of E. coli (E. coli ATCC 25922).  
Methodology: The genotoxic effects of fruit and leaf ethanolic extracts were determined by using 
enterobacterial repetitive intergenic consensus (ERIC-PCR) and sodium dodecyl sulfate 
polyacrylamide gel electrophoresis (SDS-PAGE).  
Results: The results showed an alteration in DNA and protein profiles of both tested Escherichia 
coli strains treated with fruit and leaf extracts compared with untreated control. The alterations 
ranged between decreased or increased intensity of some bands, absence or appearance of new 
amplified fragments. Moreover, increased concentrations of E. elaterium extracts and increased 
time intervals seems to yield a more profound increase in total protein concentrations in both tested
E. coli strains.  

Title

Journal of Advances in Biology & Biotechnology

Publisher

SCIENCEDOMAIN international

Publisher Country

India

Publication Type

Both (Printed and Online)

Volume

19

Year

2018

Pages

11